University Research Compliance (URC) facilitates training for the research community in order to promote compliance. All investigators and researcher personnel must complete mandatory training prior to beginning research at Oklahoma State University.

Oklahoma State University is committed to and guided by the ethical principles regarding all research involving human subjects as set forth in the report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research entitled, "Ethical Principles and Guidelines for the Protection of Human Subjects of Research".

Oklahoma State University is committed to providing an animal care and use program that provides a humane and compliant environment for all animals involved in research, teaching, and testing activities.

Oklahoma State University is commited to utilzing national codes of practice and promoting health and safety in laboratories and the community.

The university's Radiation Safety Office is charged with the responsibility to ensure that all radioactive materials and machines capable of producing ionizing radiation are used in accordance with all applicable state and federal regulations.

Oklahoma State University’s laser safety program adheres to appropriate ANSI standards with regard to Class 3B and Class 4 laser use on campus. The program is overseen by the Radiation Safety Office.

All administrators, faculty, staff, post-doctoral fellows and students who apply for, receive or serve as key personnel on a sponsored program must submit a disclosure questionnaire via the OneAegis for COI system before proposal submission at least annually during the period of award.

As an institution dedicated to excellence in education, research and outreach, Oklahoma State University places a high value on research integrity and academic freedom. Oklahoma State University takes concerns about research misconduct seriously.